参附注射液建立自发性高血压病大鼠肝阳上亢证模型的研究

目的：探讨参附注射液建立自发性高血压大鼠（SHR）模型的可能性。方法：将30只3月龄SPF级健康雄性自发性高血压大鼠称重，随机分为SHR组，附子汤组，参附注射液低、中、高剂量组，每组6只。各组采用对应药物灌胃进行模型制备，另取同品系同周龄雄性魏-凯二氏大鼠（WKY）6只作为正常对照组（WKY组）。观察参附注射液对SHR大鼠24h饮水量、易激惹程度、痛阈、睑结膜充血及收缩压的影响。结果：附子汤组及参附注射液中、高剂量组造模后均出现了易激惹程度增高、睑结膜充血程度增高、饮水量增多、痛阈降低、收缩压升高等肝阳上亢的表现，与WKY组及SHR组比较，差异有统计学意义（P<0.05)，表明造模成功。结论：参附注射液可以制备新型高血压肝阳上亢证模型，但是具体造模机制以及造模药物用量需待进一步探讨确定。     

Retrieving volume FeO and TiO_2 abundances of lunar regolith with CE-2 CELMS data using BPNN method

The volume FeO and TiO_2 abundances(FTAs) of lunar regolith can be more important for understanding the geological evolution of the Moon compared to the optical and gamma-ray results. In this paper, the volume FTAs are retrieved with microwave sounder(CELMS) data from the Chang'E-2 satellite using the back propagation neural network(BPNN) method. Firstly, a three-layered BPNN network with five-dimensional input is constructed by taking nonlinearity into account. Then, the brightness temperature(TB) and surface slope are set as the inputs and the volume FTAs are set as the outputs of the BPNN network.Thereafter, the BPNN network is trained with the corresponding parameters collected from Apollo, Luna,and Surveyor missions. Finally, the volume FTAs are retrieved with the trained BPNN network using the four-channel TBderived from the CELMS data and the surface slope estimated from Lunar Orbiter Laser Altimeter(LOLA) data. The rationality of the retrieved FTAs is verified by comparing with the Clementine UV-VIS results and Lunar Prospector(LP) GRS results. The retrieved volume FTAs enable us to re-evaluate the geological features of the lunar surface. Several important results are as follows. Firstly, very-low-Ti(1.5 wt.%) basalts are the most spatially abundant, and the surfaces with TiO_2 5 wt.% constitute less than 10% of the maria. Also, two linear relationships occur between the FeO abundance(FA) and the TiO_2 abundance before and after the threshold, 16 wt.% for FA. Secondly, a new perspective on mare volcanism is derived with the volume FTAs in several important mare basins, although this conclusion should be verified with more sources of data. Thirdly, FTAs in the lunar regolith change with depth to the uppermost surface,and the change is complex over the lunar surface. Finally, the distribution of volume FTAs hints that the highlands crust is probably homogeneous, at least in terms of the microwave thermophysical parameters.     

Petrogenesis of Early Cretaceous hornblende gabbro in Khanka Massif: evidence from geochronology and geochemistry

The authors report zircon U-Pb geochronological,whole-rock geochemical and zircon Lu-Hf isotope data for the hornblende gabbro within the Khanka Massif,with the aim of constraining its formation time and petrogenesis. The zircon U-Pb dating shows that ~(206)Pb/~(238)Pb ages of zircons from the hornblende gabbro range from 120 to 129 Ma,yielding a weighted mean age of 123 ± 2 Ma,i. e.,the Early Cretaceous. The hornblende gabbro has SiO_2 of 44. 77%--46. 58% and belongs to the tholeiitic series on FeO~t/MgO-SiO_2 diagram. It displays a right-inclined REE pattern with( La/Yb)_N ratios of 3. 44 to 4. 42. The trace element spidergram shows that they are enriched in large ion lithophile elements( LILE) such as Rb,Th,U,K and Pb,and depleted in high field strength elements( HFSE) such as Nb,Ta,Ti and P,indicating an affinity to arc igneous rocks.The ε_(Hf)( t) values of zircons vary from -2. 6 to + 3. 9 and Hf model ages( T_(DM1)) range from 622 to 883 Ma.These geochemical characteristics indicate that primary magma of the hornblende gabbro could be derived from partial melting of young mantle material accreted during the Neoproterozoic. Combined with the Early Cretaceous igneous rock assemblages in NE Asia. It is concluded that the hornblende gabbro formed in an active continental margin related to the westward subduction of the Paleo-Pacific Plate beneath the Khanka Massif.     

Explicit stress–strain equations for modeling frictional materials

In this paper, a comprehensive study on simulating the shearing behavior of frictional materials is performed. A set of two explicit equations, describing the relationship among the shear stress ratio and the distortional strain and the volumetric strain, are formulated independently. The equations contain three stress parameters and three strain parameters and another parameter representing the nonuniformity of stress and strain during softening. All the parameters have clear physical significance and can be determined experimentally. It is demonstrated that the proposed equations have the capacity of simulating the complicated shearing behavior of many types of frictional materials including geomaterials. The proposed equations are used to simulate the stress–strain behavior for 27 frictional materials with 98 tests. These materials include soft and stiff clays in both reconstituted and structured states, silicon sands and calcareous sands, silts, compacted fill materials, volcanic soils, decomposed granite soils, cemented soils (both artificially and naturally cemented), partially saturated soils, ballast, rocks, reinforced soils, tire chips, sugar, wheat, and rapeseed. It has been demonstrated that the proposed explicit constitutive equations have the capacity to capture accurately the shearing behavior of frictional materials both qualitatively and quantitatively. A study on model parameters has been performed.     

基于概率积分法的采动坡体稳定性预测与分析

地下采煤会引起地表沉降、变形,甚至引发山体、河堤滑坡等地质灾害。采动坡体的稳定性研究一直是采矿工程中实际关心的问题。该文首先介绍分析了概率积分法移动变形稳态、动态预测模型以及基于极限平衡理论的单滑面采动坡体稳定性预测模型,提出了使用概率积分法结合Knothe时间函数对采动坡体稳定性进行预测分析的方法,并使用C#及XML Schema语言编制了相关的计算程序。最后,结合一个工程实例对采动坡体稳定性和动态变化过程进行了预测与分析,通过实测数据验证了提出方法的可行性,得出了采动引起的坡体下沉是影响坡体稳定性的主要因素,并提出了在坡体拉伸阶段进行注浆加固的方法。     

Effects of stocking density on the growth and immunity of Atlantic salmon salmo salar reared in recirculating aquaculture system (RAS)

Atlantic salmon reared in recirculating aquaculture system (RAS) may lead to inappropriately high stocking density, because fish live in a limited space. Finding the suitable stocking density of Atlantic salmon reared in RAS is very important for RAS industry. In this paper, the influence of stocking density on growth and some stress related physiological factors were investigated to evaluate the effects of stocking density. The fish were reared for 220 days at five densities (A: 24 kg/m³; B: 21 kg/m³; C: 15 kg/m³; D: 9 kg/ m³ and E: 6 kg/m³ ). The results show that 30 kg/m³ might be the maximum density which RAS can afford in China. The stocking densities under 30 kg/m³ have no effect on mortality of Atlantic salmon reared in RAS. However, the specific growth rate (SGR), final weight and weight gain in the high density group were significantly lower than the lower density groups and middle density groups. Moreover, feed conversion rate (FCR) had a negative correlation with density. Plasma hormone T₃ and GH showed significant decrease with the increase of the stocking density of the experiment. Furthermore, thyroid hormone (T₃), GH (growth hormone) activities were decreased with stocking density increase. However, plasma cortisol, GOT (glutamic oxalacetic transaminase) and GPT (glutamic pyruvic transaminase) activities were increase with stocking density increase. And the stocking density has no effects on plasma lysozyme of Atlantic salmon reared in RAS. These investigations would also help devise efficient ways to rear adult Atlantic salmon in China and may, in a way, help spread salmon mariculture in China.

     

邮轮属性评价与品牌定位

以全球最大的邮轮点评网站——邮轮评论家为数据来源渠道，以编辑（Editor/Expert）的文本点评以及对167艘邮轮10大属性的打分数据为样本，利用词频分析、回归分析、聚类分析和方差分析等方法，对全球21个邮轮品牌的产品属性、总体评价以及品牌定位问题进行了系统研究。结果表明，对于专业型游客来说，餐饮、客房和娱乐是关注度最高的船上属性，服务、性价比和公共空间是满意度最高的船上属性，客房、餐饮、公共空间、性价比和娱乐属性对邮轮总评具有显著影响。方差分析表明，与行业界定下的品牌行为相比，基于专业型游客感知的品牌划分更有效。     

A case study on Landscape Component Niche based on Landscape Pattern Indices: Yanchi,Ningxia Province,China

Yanchi County is located in the agro-pastoral ecotone and belongs to the ecologically fragile area of Northwest China.It is important to study the evolution of landscape pattern to curb its environmental degradation.In order to intuitively show how the landscape pattern of the study area changes over time,Landsat Thematic Mappers(TM)and Landsat Operational Land Imager(OLI)data of 1991,2000,2010 and 2017 were used.This paper attempts to apply niche theories and methods into landscape ecology,and constructs a niche model of landscape components by using"n-dimentional hypervolume niche theory"and landscape pattern indices.By evaluating the spatial and temporal evolution of niche from the perspective of two-dimensional space to reflect the changes of landscape pattern in the study area over the past 26 years,new theories and methods were introduced for the characterization of landscape pattern.The results indicate that:1)The larger the attribute and dominance value of landscape components,the higher the ecological niche and the stronger the control effect on the overall landscape.2)The ecological niche of each landscape component was significantly different,just as its control effect on the overall landscape.3)The dynamic change of the ecological niche of each landscape component was different,with grassland,unused land and arable land always in a high dominant position,although the ecological niche of construction land and water area was always low.In general,the introduction of niche theory into the landscape ecology provided a new method to study the changes in regional landscape pattern.     

Discovery of 13 New Variable Stars in the Field of the Open Cluster NGC 2168 （M35）

A wide-field time-series CCD photometric survey of variable stars in the field of the open cluster NGC 2168 was carried out using the BATC Schmidt telescope. In total 13 new variable stars are discovered with three W UMa systems, one EA type and two EB type eclipsing binaries (one of them could be a W UMa system), and seven pulsating stars including three candidates of δScuti stars.     

Multi-wavelength Diagnostics of Bombardment by Non-thermal Particles in Solar Flares

Chromospheric lines, including Ha, Lyα, Lyβand CaⅡK, CaⅡ8542, are systemically and quantitatively investigated with respect to the non-thermal excitation and ionization due to particle beam bombardment for a series of solar semi-empirical atmospheric models. As a result we propose to use the contrast in the integrated intensity of hydrogen lines to estimate the total energy flux of the bombarding beam during the solar flare impulsive phase. Partial frequency redistribution is considered in the Lyαline calculation and a smaller intensity enhancement in the Ha line-centers is found than in the previous results of Fang et al.